What Is Methadone? Methadone is a prescription medication and a generic drug. This medication is available for sale under the brand name Methadose, Dolophine, Diskettes, and others. Methadone is an opioid medication, also known as narcotics in the streets. It is a long-acting full opioid agonist and a schedule II-controlled drug substance. Methadone is usedRead More